@Shulamit just had an awesome list about the undeniable greatness of "The Golden Girls." I had some awkward moments with Dorothy and Rose, back when I wrote for the Comedy Central Roasts. (WARNING: NSFW/ "dirty joke" stuff!)
  1. A few days before the Pam Anderson Roast. All our scripts were finished. A writer asked if I wanted to smoke pot. I foolishly said yes. An hour later - when I was super high - the show's Producer ran in: "Bea Arthur is here and wants to rehearse early! Aaron, go pitch her that anal sex joke!"
    3a97dc6d 737c 4327 ab2d 8a511034a084
    I found Bea onstage. My heart was racing. I introduced myself, then asked if she would deliver a joke with the punchline, "I wonder what it feels like... To hold in a fart." Bea physically recoiled from me, letting out a massive "UCCCCCHHHH!" of disgust. I slumped away, shaking.
  2. The William Shatner Roast. This time, I was ordered to pitch a joke to Betty White where the punchline was, "I popped Shatner's dick out of my mouth and said 'Bill, it's time to start the roast.'" I approached her, took a deep breath and pitched the joke.
    F2c26c57 bd25 4334 b01f af8d2ef39e60
    She listened intently. When I reached the punchline, she smiled sweetly and - on a dime - replied, "I never talk with my mouth full, dear." I fell in love.
  3. Here's what Betty White ended up saying instead.
    3bfa03b6 4976 4f0b a5b1 c58ebd7f4085
  4. Addendum: Bea and Betty both destroyed on the roasts, and received standing ovations.