1. Someone faced with adversity (e.g., a disability) learns to play an instrument beautifully
    Extra tears if their parent or parents told them they'd never be able to
  2. An elderly person has dementia and forgets his or her children
  3. A kid that is allergic to bees gets stung by a lot of bees and dies
  4. Members of two different species become unlikely friends
    See: Milo and Otis, Charlotte's Web
  5. Someone is wrongfully accused of a crime
    This one is mainly because I start having a panic attack thinking about what I would do if that happened to me
  6. A sports team made up of underdogs wins the big game
  7. The song "Mad World" plays
  8. Someone that is married with children realizes that they are very unhappy
    I just can't imagine what it's like to wake up one day, your life has passed you by, and you realize it hasn't turned out how you planned.
  9. A child whose parents can't normally afford to provide them with a Christmas gets a "Christmas miracle" and gets a lot of presents and is so happy
  10. A bully ends up realizing the error of their ways and apologizes to someone they have been bullying
  11. A child says goodbye to a parent forever
    I once was instantly in tears when I flipped to Armageddon at the wrong time
    Suggested by @edoublebubs
  12. Childhood friends reconnect later in life and fall in love
    Suggested by @migmags
  13. A character is going through a tough time and speaks out loud to their dead parent who they wish was there to help them.
    Suggested by @migmags
  14. An adult identifies with a lonely child and becomes the person that they never had.
    See: Now, Voyager
    Suggested by @moonjockey