ROAD TRIPPING SOUTH - SUGGESTIONS?

I'm headed down south in July and would love some inside scoop, must sees or other recommendations. Also! Good places to stop in between. This is the very loose route we're thinkin...
  1. NYC to Floyd, Virginia
  2. Floyd, Virginia to Charleston, SC
  3. Charleston to (?), Alabama
  4. (?), Alabama to New Orleans
  5. New Orleans to Memphis
  6. Memphis to Nashville
  7. Nashville to (?)
  8. (?) to NYC