1. Randy Quaid's Cameltoe (National Lampoon's Christmas Vacation)
  2. Edward Norton's Lisp (Everything)
    I would still pay to listen to him read the phone book
  3. The way Jim Carrey says the long "o" in "sorry" like the Canadian he is
    Suggested by @BWN_7
  4. When an actor is handed a bag, or a suitcase, or a box, or even a cup/glass, and it's so obviously empty - but they have to pretend like it isn't and I can totally tell.
    Suggested by @BWN_7