It'd be impossible to sum up this huge city's entire shopping scene, but this is our rough guide of the places worth browsing—whether you're a tourist or an NYC lifer—organized from north to south.
  1. Otte
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    Inside this Upper East Side flagship, there's no shortage of mid- to high-range brands like Acne, Isabel Marant, and Thakoon.
  2. Goyard
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    The townhouse displays signature trunks, purses, and other leather goods in a two-story manse as stately as its products' price tags.
  3. Barneys New York
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    Barneys' decidedly unstuffy approach to high-end style makes it a favorite of fashion types, from ladies who lunch to downtown hipsters and everyone in between.
  4. Bergdorf Goodman
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    Bergdorf Goodman is known for lavish window displays, world-class designer shopping, and the 9th floor John Barrett salon.
  5. Saks Fifth Avenue
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    Saks Fifth Avenue has been undergoing a major retail revival over the past few years. Smaller projects include the return of its awnings and a new designer sneaker shop.
  6. Comme des Garçons
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    A high-fashion boutique designed by Dr. Seuss, this Chelsea stalwart underwent a major golden makeover at the end of 2013.
  7. STORY
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    Story describes itself as "a retail space that has the point of view of a magazine, changes like a gallery and sells things like a store."
  8. Dover Street Market New York
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    Located in a neighborhood that's not known for its fashion, this is the epitome of the high-end boutique alternative to Manhattan's traditional concept of a department store.
  9. Diane von Furstenberg
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    Diane von Furstenberg's Meatpacking flagship really embraces the idea that a boutique's design should reflect the message of its clothes.
  10. Housing Works Thrift Shop
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    The Chelsea location looks like a designer store, and it's a really good place to find deals on great furniture and clothing while supporting a good cause.
  11. Owen
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    Owen has developed a loyal clientele, thanks to its mix of established contemporary designers and hip, under-the-radar brands.
  12. ABC Carpet & Home
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    This home decor mecca maintains a warehouse-chic aesthetic for decorators who like their high-end antiques to come with a bit of character.
  13. C.O. Bigelow
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    The 177-year-old pharmacy is notable for its selection of hard-to-find beauty products, including European imports and a well-loved house line.
  14. The Strand
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    This iconic establishment houses thousands of discounted new and used titles, rare books, and hard-to-find art and photography tomes.
  15. Kiehl's
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    This apothecary is obsessively modern, from its simple recyclable packaging to its frequently-updated line of magical skincare products.
  16. Bond No. 9
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    Shop the flagship location for scents dedicated to our city's diverse neighborhoods, all available in the same uniquely shaped bottle.
  17. Oak
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    Lines like Pleasure Principle and Grey Ant mingle with the store's in-house label, a lower-priced offshoot called A.Ok that offers a mix of clothing and accessories.
  18. Birchbox
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    A beauty junkie's paradise, Birchbox is stocked with more than 2,000 products, touch-screen tools and makeup classes.
  19. & Other Stories
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    Merchandise includes apparel, shoes, bags, and even bath products—and it all looks much more expensive than its affordable price tags relay.
  20. COS
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    The Swedish-minimal label turns out perfect basics, the best of which could pass for Céline. Bonus: the store is home to a haunted well.
  21. What Goes Around Comes Around
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    There's nothing twee about this Soho vintage shop, which has made a name for itself with an enormous selection of designer pieces.
  22. Kirna Zabete
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    Kirna Zabete has always had its finger on the pulse of what shoppers will love from their favorite high-end names and some new labels.
  23. Broken English
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    The L.A. fine jewelry opened its first-ever NY shop last summer in Soho. Be sure to check out the shop’s on-point vintage jewelry picks, too.
  24. Creatures Of Comfort
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    Owner Jade Lai has terrific taste and a killer eye for color, as embodied by her shop's selection of cool-kid labels and the house line.
  25. Trademark
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    Pookie and Louisa Burch (daughters of Chris Burch and former step-daughters of Tory Burch) brought their label to Grand Street last summer.
  26. Warm
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    The boutique is particularly cozy inside, and boasts a well-edited selection of clothing from designers like Giada Forte and Ryan Roche.
  27. Veda
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    Veda designer Lyndsey Butler opened up this outpost in 2013 - meaning every single style from their website is in reach, even if it's not on the racks.
  28. American Two Shot
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    American Two Shot is as cool a place to hang out as it is to shop, thanks to the Café Integral coffee bar in the front of the store.
  29. Opening Ceremony
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    Currently the destination for it-labels like Kenzo, Opening Ceremony has benefited from major publicity in magazines and blogs.
  30. Steven Alan Annex
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    The store is filled with plaid shirts for men and gamine looks for women, plus a carefully selected collection of pieces from like-minded brands like APC.
  31. Space Ninety 8
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    The Urban Outfitters concept store in Williamsburg has a Market Space with local artisans, the Urban Renewal section, and the basement pop-up shop.
  32. Pilgrim Surf + Supply
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    Step into this airy Williamsburg shop and find yourself transported to a place that makes you want to use the world "chill."
  33. Beam
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    The space is stocked with conversation starters like purple velvet Chesterfields, constellation-print plates, and punched-metal pendant lamps.
  34. Catbird
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    In addition to its popular in-house line, Catbird sells jewelry by local designers, as well as a selection of beauty products.
  35. Bird
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    The space carries Rag & Bone and other designers so of-the-moment that if you only shopped there for the rest of your life, you'd still look hip.
  36. Swords-Smith
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    This Williamsburg boutique sells both men's and women's clothing and accessories from indie labels alongside their own in-house line.
  37. Brooklyn Flea
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    Brooklyn Flea is now basically everywhere. But regardless of its ubiquity, the OG flea is still a great place to find cute clothing, accessories, and home goods.
  38. Article&
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    Inside, you'll find the best of the new store's selection of cool, contemporary brands and the same sweet, attentive service.