It'd be impossible to sum up this huge city's entire shopping scene, but this is our rough guide of the places worth browsing—whether you're a tourist or an NYC lifer—organized from north to south.
  1. 1.
    Inside this Upper East Side flagship, there's no shortage of mid- to high-range brands like Acne, Isabel Marant, and Thakoon.
  2. 2.
    The townhouse displays signature trunks, purses, and other leather goods in a two-story manse as stately as its products' price tags.
  3. 3.
    Barneys New York
    Barneys' decidedly unstuffy approach to high-end style makes it a favorite of fashion types, from ladies who lunch to downtown hipsters and everyone in between.
  4. 4.
    Bergdorf Goodman
    Bergdorf Goodman is known for lavish window displays, world-class designer shopping, and the 9th floor John Barrett salon.
  5. 5.
    Saks Fifth Avenue
    Saks Fifth Avenue has been undergoing a major retail revival over the past few years. Smaller projects include the return of its awnings and a new designer sneaker shop.
  6. 6.
    Comme des Garçons
    A high-fashion boutique designed by Dr. Seuss, this Chelsea stalwart underwent a major golden makeover at the end of 2013.
  7. 7.
    Story describes itself as "a retail space that has the point of view of a magazine, changes like a gallery and sells things like a store."
  8. 8.
    Dover Street Market New York
    Located in a neighborhood that's not known for its fashion, this is the epitome of the high-end boutique alternative to Manhattan's traditional concept of a department store.
  9. 9.
    Diane von Furstenberg
    Diane von Furstenberg's Meatpacking flagship really embraces the idea that a boutique's design should reflect the message of its clothes.
  10. 10.
    Housing Works Thrift Shop
    The Chelsea location looks like a designer store, and it's a really good place to find deals on great furniture and clothing while supporting a good cause.
  11. 11.
    Owen has developed a loyal clientele, thanks to its mix of established contemporary designers and hip, under-the-radar brands.
  12. 12.
    ABC Carpet & Home
    This home decor mecca maintains a warehouse-chic aesthetic for decorators who like their high-end antiques to come with a bit of character.
  13. 13.
    C.O. Bigelow
    The 177-year-old pharmacy is notable for its selection of hard-to-find beauty products, including European imports and a well-loved house line.
  14. 14.
    The Strand
    This iconic establishment houses thousands of discounted new and used titles, rare books, and hard-to-find art and photography tomes.
  15. 15.
    This apothecary is obsessively modern, from its simple recyclable packaging to its frequently-updated line of magical skincare products.
  16. 16.
    Bond No. 9
    Shop the flagship location for scents dedicated to our city's diverse neighborhoods, all available in the same uniquely shaped bottle.
  17. 17.
    Lines like Pleasure Principle and Grey Ant mingle with the store's in-house label, a lower-priced offshoot called A.Ok that offers a mix of clothing and accessories.
  18. 18.
    A beauty junkie's paradise, Birchbox is stocked with more than 2,000 products, touch-screen tools and makeup classes.
  19. 19.
    & Other Stories
    Merchandise includes apparel, shoes, bags, and even bath products—and it all looks much more expensive than its affordable price tags relay.
  20. 20.
    The Swedish-minimal label turns out perfect basics, the best of which could pass for Céline. Bonus: the store is home to a haunted well.
  21. 21.
    What Goes Around Comes Around
    There's nothing twee about this Soho vintage shop, which has made a name for itself with an enormous selection of designer pieces.
  22. 22.
    Kirna Zabete
    Kirna Zabete has always had its finger on the pulse of what shoppers will love from their favorite high-end names and some new labels.
  23. 23.
    Broken English
    The L.A. fine jewelry opened its first-ever NY shop last summer in Soho. Be sure to check out the shop’s on-point vintage jewelry picks, too.
  24. 24.
    Creatures Of Comfort
    Owner Jade Lai has terrific taste and a killer eye for color, as embodied by her shop's selection of cool-kid labels and the house line.
  25. 25.
    Pookie and Louisa Burch (daughters of Chris Burch and former step-daughters of Tory Burch) brought their label to Grand Street last summer.
  26. 26.
    The boutique is particularly cozy inside, and boasts a well-edited selection of clothing from designers like Giada Forte and Ryan Roche.
  27. 27.
    Veda designer Lyndsey Butler opened up this outpost in 2013 - meaning every single style from their website is in reach, even if it's not on the racks.
  28. 28.
    American Two Shot
    American Two Shot is as cool a place to hang out as it is to shop, thanks to the Café Integral coffee bar in the front of the store.
  29. 29.
    Opening Ceremony
    Currently the destination for it-labels like Kenzo, Opening Ceremony has benefited from major publicity in magazines and blogs.
  30. 30.
    Steven Alan Annex
    The store is filled with plaid shirts for men and gamine looks for women, plus a carefully selected collection of pieces from like-minded brands like APC.
  31. 31.
    Space Ninety 8
    The Urban Outfitters concept store in Williamsburg has a Market Space with local artisans, the Urban Renewal section, and the basement pop-up shop.
  32. 32.
    Pilgrim Surf + Supply
    Step into this airy Williamsburg shop and find yourself transported to a place that makes you want to use the world "chill."
  33. 33.
    The space is stocked with conversation starters like purple velvet Chesterfields, constellation-print plates, and punched-metal pendant lamps.
  34. 34.
    In addition to its popular in-house line, Catbird sells jewelry by local designers, as well as a selection of beauty products.
  35. 35.
    The space carries Rag & Bone and other designers so of-the-moment that if you only shopped there for the rest of your life, you'd still look hip.
  36. 36.
    This Williamsburg boutique sells both men's and women's clothing and accessories from indie labels alongside their own in-house line.
  37. 37.
    Brooklyn Flea
    Brooklyn Flea is now basically everywhere. But regardless of its ubiquity, the OG flea is still a great place to find cute clothing, accessories, and home goods.
  38. 38.
    Inside, you'll find the best of the new store's selection of cool, contemporary brands and the same sweet, attentive service.